LOCATION United States

San Isidro, Texas

San Isidro is a census-designated place (CDP) in Starr County, Texas, United States. The population was 240 at the 2010 census. The town is named for St. Isidore the Laborer, the patron saint of farmers. A large Southwestern Barrel Cactus growing just east of town is said to be the largest in Texas.

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